Open Positions

Studies of Pain Mechanisms and Circuits for Development of Therapeutics

Exciting opportunity for a motivated postdoctoral associate to join the Seal lab studying spinal pain circuits and developing novel viral therapies based on your discoveries.

The successful candidate will perform patch clamp electrophysiology with channelrhodopsin stimulation and viral monosynaptic tracing to identify connectivity to major dorsal horn pain circuits. The candidate will use the findings to design adeno-associated viruses as novel pain therapeutics for testing in non-human primates.

The laboratory is in the Department of Neurobiology at the University of Pittsburgh School of Medicine and is affiliated with the University of Pittsburgh Brain Institute, the Pittsburgh Center for Pain Research, and the Center for the Neural Basis of Cognition. The successful candidate will have many opportunities to interact with faculty, postdocs and graduate students within these associated groups and across the university as well as at local and international scientific meetings.

As a member of the Seal laboratory, you will be part of a culture that values hard work, intellectual curiosity, creativity, innovative thinking and teamwork, thus making it a wonderful place to grow and develop professionally.

PhD in Neuroscience, Physiology or equivalent with 0-3 years postdoc experience.
Expertise in patch clamp electrophysiology preferred.

Please send your CV with the names and contact info for three references to Dr. Rebecca Seal,

For more information on our research please visit our website:


Studies of Motor Function in Parkinson’s Disease

Postdoctoral position is available to study mechanisms of striatal plasticity that underly motor impairment in Parkinson’s disease in vitro and in vivo. We are focused on identifying novel forms of plasticity that correct the motor impairments in Parkinson’s disease. Our laboratory uses cutting-edge techniques such as chemogenetics, optogenetics with behavior and electrophysiology as well as morphological analysis with two-photon and confocal microscopy.

The Position requires a Ph.D. in Neuroscience, Physiology or related field within the past 0-2 years as well as enthusiasm for high quality science and good communication skills. Patch clamp electrophysiology experience is a plus.

The laboratory is located in the University of Pittsburgh School of Medicine and is affiliated with the Pittsburgh Brain Institute, the Department of Neurobiology and the Center for the Neural Basis of Cognition. The lab is part of a large, vibrant, multidisciplinary and internationally recognized neuroscience community that includes Carnegie Mellon.

Pittsburgh is a fun, modern and attractive city that offers numerous cultural and sports activities as well as a truly affordable lifestyle. It is consistently rated Most Livable City in the US by the Economist and Forbes Magazine.

Please send your CV and brief description of your career goals and research experience to