Open Positions

Studies of Pain Mechanisms and Neural Circuits for the Development of Novel Therapeutics

A fully-funded postdoc position is open in the Seal laboratory to identify the neural circuitry underlying persistent forms of pain using vivo calcium imaging, and viral monosynaptic tracing and optogenetic/ chemogenetic analysis as well as in vitro patch clamp electrophysiology with channelrhodopsin stimulation. Opportunity to develop novel pain therapies is also possible. Successful candidate will also have the opportunity to present work at local and international scientific meetings (e.g. Society for Neuroscience, American Pain Society, International Association for the Study of Pain).

As a member of the laboratory, you will be part of a culture that values hard work, intellectual curiosity, innovative thinking, teamwork and professional development.

Ph.D. in Neuroscience, Physiology or equivalent with 0-3 years postdoc experience.
Expertise in patch clamp electrophysiology preferred.

The laboratory is in the Department of Neurobiology within the School of Medicine and is closely affiliated with the Brain Institute (UPBI), the Pittsburgh Center for Pain Research (PCPR), and the Center for the Neural Basis of Cognition (CNBC), CNBC is a joint program between the University of Pittsburgh and Carnegie Mellon. Through these affiliations, you will have the opportunity to interact directly with exceptional faculty, postdocs and graduate students sharing similar interests.

The University of Pittsburgh is currently ranked third in NIH funding. And Pittsburgh is ranked second Most Livable City in America, according to The Global Livability Index 2018 (The Economist).

Please email a brief statement of research interests and CV to Dr. Rebecca Seal (

For more information on our research please visit our website: and the Pittsburgh Center for Pain Research:


Studies of the Plasticity Mechanisms Underlying the Motor Symptoms in Parkinson’s Disease

Postdoctoral position is available to study mechanisms of striatal plasticity that underly motor impairment in Parkinson’s disease in vitro and in vivo. We are focused on identifying novel forms of plasticity that correct the motor impairments in Parkinson’s disease. Our laboratory uses cutting-edge techniques such as chemogenetics, optogenetics with behavior and electrophysiology as well as morphological analysis with two-photon and confocal microscopy.

The Position requires a Ph.D. in Neuroscience, Physiology or related field within the past 0-2 years as well as enthusiasm for high quality science and good communication skills. Patch clamp electrophysiology experience is a plus.

The laboratory is located in the University of Pittsburgh School of Medicine and is affiliated with the Pittsburgh Brain Institute, the Department of Neurobiology and the Center for the Neural Basis of Cognition. The lab is part of a large, vibrant, multidisciplinary and internationally recognized neuroscience community that includes Carnegie Mellon.

Pittsburgh is a fun, modern and attractive city that offers numerous cultural and sports activities as well as a truly affordable lifestyle. It is consistently rated Most Livable City in the US by the Economist and Forbes Magazine.

Please send your CV and brief description of your career goals and research experience to


The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EEO/AA/M/F/Vets/Disabled